Glycemic Excursions in Type 1 Diabetes in Pregnancy: A Semiparametric Statistical Approach to Identify Sensitive Time Points during Gestation

Figure 2

Fitted glucose curves of women with type 1 diabetes based on semiparametric regression modeling using penalized regression splines to estimate the rate of change in glucose (-axis, mg/dL) against gestation time (-axis, in days). The solid line represents fitted maternal glycemic profiles of mothers who gave birth to LGA infants; the dashed line represents fitted maternal glycemic profiles of mothers who gave birth to AGA infants.