Research Article

HbA1c-Based Score Model for Predicting Death Risk in Patients with Hepatocellular Carcinoma and Type 2 Diabetes Mellitus

Table 1

Characteristics of patients.

VariableTotal patients
()
Survival group
()
Death group
value

Age (yr)58.93 ± 9.5056.80 ± 10.1560.06 ± 8.980.050
Male sex116 (78.9)42 (82.4)74 (77.1)0.456
History of smoking57 (40.1)23 (45.1)34 (35.4)0.288
History of alcohol use47 (32.0)16 (31.4)31 (32.3)1.000
Family history of liver disease35 (23.8)11 (21.6)24 (25.0)0.689
Family history of diabetes6 (4.1)3 (5.9)3 (3.1)0.418
WBC (×109/L)5.0 ± 2.74.4 ± 2.15.3 ± 2.9<0.001
NLR3.0 (1.8, 5.3)1.9 (1.5, 3.1)4.1 (2.1, 6.7)<0.001
PLT (×109/L)79.8 (53.4, 148.9)83.0 (59.0, 122.3)79.2 (50.8, 156.8)0.880
HGB (g/l)116.1 ± 23.5123.9 ± 24.0112.0 ± 22.3<0.001
ALT (U/L)33.7 (22.5, 55.1)32.6 (21.5, 50.5)34.3 (25.2, 59.4)0.490
TBIL (μmol/l)21.9 (12.3, 42.1)15.8 (9.7, 26.3)29.6 (15.2, 64.6)<0.001
GGT (U/L)70.5 (34.0, 146.2)49.5 (29.0, 96.3)86.5 (42.3, 198.5)<0.001
ALB (g/l)33.7 ± 6.337.2 ± 6.031.9 ± 5.6<0.001
TC (mmol/L)3.5 (2.8, 4.2)3.8 (3.0, 4.2)3.3 (2.8, 4.1)0.170
HDLC (mmol/L)1.0 ± 0.51.2 ± 0.40.9 ± 0.5<0.001
HbA1c (%)7.0 ± 2.06.4 ± 1.97.4 ± 2.00.010
Cr (μmol/l)64.0 (54.0, 77.0)62.0 (53.0, 71.0)66.0 (54.3, 85.3)0.040
PT (s)14.1 ± 2.813.4 ± 2.714.5 ± 2.8<0.001
AFP (ng/ml)15.2 (4.7, 169.2)16.8 (4.6, 83.3)15.1 (5.5, 280.8)0.390
MELD score22.4 ± 7.019.8 ± 5.623.8 ± 7.3<0.001
CTP class (A/B/C)53/51/4331/12/822/39/35<0.001