The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population
Table 1
The clinical characteristics of DKD group and control group.
Characteristic
Control subjects
Diabetic kidney disease
value
Male/female
719/570
326/209
0.0427
Age (years)
57.88 ± 9.81
60.14 ± 9.84
0.0051
BMI (kg/m2)
24.82 ± 3.53
25.02 ± 3.49
0.3047
Duration of diabetes (years)
10 (7, 14)
10 (6, 15)
0.8527
HbA1C (%)
8.75 ± 2.07
8.85 ± 2.11
0.3727
SBP (mmHg)
131.04 ± 16.28
135.45 ± 17.36
<0.0001
DBP (mmHg)
79.92 ± 9.21
81.31 ± 9.61
0.0127
MA (mg/24h)
10.85 (6.41, 25.17)
58.13 (33.79, 157.16)
<0.0001
eGFR (mL/kg/1.73 m2)
132.89 (115.95, 154.12)
101.59 (80.2, 132.25)
<0.0001
Uric acid (μmol/L)
301.0 (255.0, 359.0)
346.0 (287.0, 413.0)
<0.0001
Creatinine (μmol/L)
63 (53.37, 73.54)
80.12 (64.49, 101.29)
<0.0001
Blood urea nitrogen (mmol/L)
5.14 (4.23, 6.01)
6.04 (4.91, 7.53)
<0.0001
TC (mmol/L)
1.70 ± 1.4
2.11 ± 2.01
0.0467
TG (mmol/L)
4.70 ± 1.08
4.87 ± 1.37
<0.0001
Data are shown as the mean ± SD or median (interquartile range). The Wilcoxon test was used for the skewed distributed variables. χ2 test was used to determine proportions of the categorical variables. values < 0.05 are shown in bold. DKD: diabetic kidney disease. BMI: body mass index. SP: systolic blood pressure. DP: diastolic blood pressure. MA: microalbuminuria. eGFR: estimated glomerular filtration rate. TC: total cholesterol. TG: total triglycerides.
