The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population
Table 2
The clinical characteristics of diabetic retinopathy group and control group.
Characteristic
Control subjects
Diabetic retinopathy
value
Male/female
628/492
319/226
0.3414
Age (years)
58.56 ± 9.87
57.76 ± 9.24
0.0473
BMI (kg/m2)
24.88 ± 3.53
24.84 ± 3.50
0.6125
Duration of diabetes (years)
9 (5, 12)
11 (8, 16)
<0.0001
HbA1C (%)
8.82 ± 2.1
8.80 ± 2.05
0.8048
SBP (mmHg)
130.67 ± 16.01
135.24 ± 17.68
<0.0001
DBP (mmHg)
80.35 ± 9.25
80.41 ± 9.29
0.8808
MA (mg/24h)
7.31 (3.46, 19.64)
8.34 (3.95, 26.33)
0.0484
eGFR (mL/kg/1.73 m2)
126.08 (106.75, 148.52)
128.75 (105.72, 151.72)
0.7612
Uric acid (μmol/L)
309.5 (258.0, 369.0)
317.0 (269.0, 372)
0.1255
Creatinine (μmol/L)
65.5 (54.0, 78.0)
66.0 (55.0, 78.0)
0.4402
Blood urea nitrogen (mmol/L)
5.3 (4.4, 6.3)
5.3(4.4, 6.4)
0.8090
TC (mmol/L)
1.84 ± 1.72
1.80 ± 1.72
0.8687
TG (mmol/L)
4.77 ± 1.15
4.76 ± 1.21
0.4843
Data are shown as the mean ± SD or median (interquartile range). The Wilcoxon test was used for the skewed distributed variables. χ2 test was used to determine proportions of the categorical variables. values < 0.05 are shown in bold. DKD: diabetic kidney disease. BMI: body mass index. SP: systolic blood pressure. DP: diastolic blood pressure. MA: microalbuminuria. eGFR: estimated glomerular filtration rate. TC: total cholesterol. TG: total triglycerides.
