Relationship of Hyperglycaemia, Hypoglycaemia, and Glucose Variability to Atherosclerotic Disease in Type 2 Diabetes

Table 4

Laboratory findings of subjects with and without macrovascular disease.

Variable	No macrovascular disease ()	Macrovascular disease ()	value
White cell count (×10^9/L)^†	7.09 (5.88–7.87)	7.29 (6.42–9.24)	0.13
Haemoglobin (g/dL)^†	14.2 (13.3–15.1)	14.4 (13.6–15.2)	0.48
Platelet count (×10^9/L)^†	242 (204.5–283.5)	239 (206–287)	0.78
RDW (%)^†	13 (12.5–13.45)	13.1 (12.6–13.8)	0.13
MPV (fL)^†	10.95 (10.23–11.5)	10.9 (10.1–11.6)	0.53
eGFR (mL/min/1.72 m^2)	87.76 ± 22.21	93.58 ± 26.0	0.19
Total cholesterol (mmol/L)^†	4.14 (3.65–5.25)	4.1 (3.53–5.11)	0.80
HDL cholesterol (mmol/L)^†	1.32 (1.1–1.58)	1.24 (1.04–1.46)	0.07
LDL cholesterol (mmol/L)^†	2.3 (1.65–3.36)	2.18 (1.7–3.13)	0.81
Non-HDL cholesterol (mmol/L)^†	2.74 (2.18–3.86)	2.83 (2.29–3.78)	0.67
Triglycerides (mmol/L)^†	1.13 (0.91–1.64)	1.47 (1.14–1.85)	0.03
ALP (mmol/L)^†	66 (52–93)	69 (59.25–80)	0.89
ALT (mmol/L)^†	22 (17.5–32)	24 (18–32.75)	0.6
Uric acid (μmol/L)	319.56 ± 83.19	308.65 ± 78.03	0.47
ESR (mm 1st hr)^†	13 (7–23)	9 (5–17)	0.08
FPG (mmol/L)^†	7.14 (6.02–8.53)	7.08 (6.23–8.05)	0.55
Fructosamine (μmol/L)^†	281 (259.25–305)	277 (256–303.5)	0.77
HbA1c (%)^†	7.0 (6.3–8.1)	6.7 (6.3–7.4)	0.23
HbA1c (mmol/L)^†	53 (45–65)	50 (45–57)	0.23

Values are expressed as mean ± SD or ^†median (IQR). Abbreviations: ALP: alkaline phosphatase; ALT: alanine transaminase; eGFR: estimated glomerular filtration rate; ESR: erythrocyte sedimentation rate; FPG: fasting plasma glucose; HbA_1c: glycated haemoglobin; MPV: mean platelet volume; RDW: red blood cell distribution width.