Research Article
Low Birth Weight, Cumulative Obesity Dose, and the Risk of Incident Type 2 Diabetes
Table 2
Unadjusted hazard ratios (HRs) of developing diabetes using univariate Cox regression analyses.
| | Characteristic | Levels | N (%) | Unadjusted HR (95% CI) | value |
| | Ethnicity () | Others | 251 (2.22) | Reference | | | White | 11,065 (97.78) | 0.575 (0.306, 1.081) | 0.0856 |
| | Sex () | Females | 8034 (48.48) | Reference | | | Males | 8539 (51.52) | 1.389 (1.131, 1.704) | 0.0017 |
| | Birth weight () | Normal | 12,761 (84.83) | Reference | | | Low birth weight | 879 (5.84) | 1.408 (0.942, 2.104) | 0.0948 | | High birth weight | 1403 (9.33) | 1.138 (0.801, 1.618) | 0.4695 |
| | Social class () | I (professional occupations) | 654 (4.43) | Reference | | | II (managerial and technical occupations) | 1934 (13.10) | 1.332 (0.639, 2.777) | 0.4446 | | III (skilled occupations) | 8943 (60.57) | 1.963 (1.007, 3.825) | 0.0476 | | IV (partly skilled occupations) | 1809 (12.25) | 2.159 (1.058, 4.406) | 0.0344 | | V (unskilled occupations) | 1424 (9.65) | 2.543 (1.227, 5.271) | 0.0121 |
| | Cumulative obesity dose () | 10-unit increase | | 1.076 (1.068, 1.084) | <0.0001 |
| | Time-varying BMI () | 1-unit increase | | 1.098 (1.081, 1.115) | <0.0001 |
| | Last BMI () | 1-unit increase | | 1.137 (1.078, 1.198) | <0.0001 |
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indicates significance at 0.05 level.
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