Association between Early Neuroretinal Dysfunction and Peripheral Motor Unit Loss in Patients with Type 1 Diabetes Mellitus

Table 1

Clinical and laboratory characteristics of controls (C) and subjects with diabetes (T1DM), mean (SD).

	C	T1DM	value
Gender (M/W)	5/9	9/11
Age (yrs)	39.07 (14.4)	42.3 (12.4)
Diabetes duration (yrs)	—	17.9 (9.5)	—
BMI (kg/m^2)	22.5 (±2)	24.9 (± 2.5)
Glycemia (mmol/l)	4.9 (0.6)	8.9 (1.4)
HbA1c (%) (mmol/mol)	—	7.5 (0.8); 58 (15)	—
Tot chol (mmol/l)	4.0 (0.6)	4.3 (0.44)
HDL chol (mmol/l)	1.7 (0.2)	1.5 (0.2)
Trigl (mmol/l)	0.8 (0.1)	0.75 (0.1)
Microalb/creat (mg/gr)	—	7.2 (5.2)	—
Sural nerve (lateral malleolus)	—	Distal SNAP amp (μV); 13.4 (±4.3)	—
		SCV (ms); 56.4 (±6.9)	—
Tibial nerve (AH)	—	Distal CMAP latency (ms); 3.2 (±0.4)	—
		Distal cMAP amplitude (μV); 11.9 (±4.6)	—
		MCV (ms); 47.3 (±4.5)	—
Ulnar nerve (ADM)	—	Distal CMAP latency (ms); 2.2 (±1.7)	—
		Distal cMAP amplitude (μV); 9.8 (±1.7)	—
		MCV (ms); 59.7 (±5.3)	—

No patient showed abnormalities (temporal dispersion or conduction block) in intermediate and proximal nerve segments. M: men; W: women; BMI: body mass index; HbA1c: hemoglobin glycated; Tot chol: total cholesterol; HDL chol: high-density lipoprotein cholesterol; Trigl: triglycerides; Microalb/creat: microalbuminuria/creatininuria; AH: abductor hallux; ADM: abductor digiti minimi; SNAP: sensory nerve action potential; MCV: motor conduction velocity; SCV: sensory conduction velocity; -test. Statistical significance .