Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy

Table 2

Characteristics of patients with different HIF-1A variants.

	Total	CC	CT	TT	value
	703	591	87	25
Women/men ()	305/398	260/331	34/53	11/14	0.688
Age (years)					0.586
BMI (kg/m^2)					0.752
Diabetes duration (years)					0.638
HbA1c (mmol/mol)					0.895
e-GFR (mL/min/1.73 m^2)					0.376
Height (cm)					0.762
Systolic blood pressure (mmHg)					0.898
Diastolic blood pressure (mmHg)					0.828
TG (mg/dL)					0.730
Cholesterol (mmol/L)					0.966
LDL (mmol/L)					0.252
HDL (mmol/L)					0.242
Smoking ()	85 (12%)	74 (13%)	9 (10%)	2 (8%)	0.689
Antihypertensive treatment ()	321 (46%)	276 (47%)	34 (39%)	11 (44%)	0.511

Data are shown as . The differences between the three groups were tested using the Kruskal-Wallis test. CC, CT, and TT are the genotypes of the HIF-1A Pro582Ser polymorphism. ns, nonsignificant; BMI, body mass index; HbA1c, glycated hemoglobin; e-GFR, estimated glomerular filtration rate; TG, triglycerides; LDL, low-density lipoprotein; HDL, high-density lipoprotein.