Research Article

The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach

Table 2

Fatty acid composition for the NEFA lipid class in Wistar () and HHTg rats () at 3 months of age.

W-3 m (% of total fatty acids)HHTg-3 m (% of total fatty acids) value

16:00n.s.
18:00<0.05
16:1n7<0.01
18:2n6n.s.
20:3n6<0.001
20:4n6n.s.
20:5n3<0.05
22:5n3<0.001
SFA<0.05
MUFAn.s.
n-6 PUFAn.s.
n-3 PUFA<0.01

Values are given as ; for each group. The relative concentration of each fatty acid was calculated as a proportion of all of the fatty acids detected: percentage of total fatty acids. Statistical significance was calculated by Student’s -test. W: Wistar control rats, HHTg: hereditary hypertriglyceridemic rats, SFA: saturated fatty acids, MUFA: monounsaturated fatty acids, PUFA: polyunsaturated fatty acids.