Research Article

The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach

Table 3

Serum adipokines, proinflammatory parameters, and basal renal markers in Wistar control () and HHTg rats () at the age of 3 months before microalbuminuria onset.

W-3 mHHTg-3 m value

Adiponectin (μg/ml)n.s.
Leptin (μg/ml)<0.05
TNF-α (pg/ml)n.s.
IL-6 (pmol/l)n.s.
MCP-1 (pmol/l)<0.05
Creatinine (mmol/l)n.s.
Uric acid (μmol/l)n.s.

Values are given as ; for each group. Statistical significance was calculated by Students -test. W: Wistar control rats, HHTg: hereditary hypertriglyceridemic rats, TNF-α: tumour necrosis factor α, IL-6: interleukin 6, MCP-1: monocyte chemoattractant protein-1.