Pathological Features of Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats

Figure 11

The mean area ratios of glial fibrillary acidic protein (GFAP) and vascular endothelial growth factor (VEGF) positivity ((a) GFAP; (b) VEGF) in the three rat types. Quantitative analysis shows that the GFAP and VEGF immunopositive regions in the retinas of Spontaneously Diabetic Torii (SDT) fatty rats are significantly larger than those of the SDT rats. The data are expressed as the . and , SDT fatty rats vs. SDT rats; ^### and ^####, SDT fatty rats vs. Sprague Dawley (SD) rats; ^† and ^††, SDT rats vs. SD rats by Scheffe’s test. ^§, ^§§, and ^§§§, SDT fatty rats vs. SDT rats by Mann–Whitney -test.

(a)

(b)