Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult

Figure 1

Cell cytotoxicity of GLP-1 receptor agonists (GLP-1RAs) in dorsal root ganglion (DRG) neurons. Cytotoxicity was determined 24 hours after treatment with GLP-1RAs or forskolin using LDH assay. No significant difference was detected between neurons treated with GLP-1RAs or forskolin and those without treatment (control). Concentrations of GLP-1RAs; exendin-4: 0.1, 1, 10, and 100 nM; GLP-1: 1, 10 nM. Ctrl: control; Fskln: forskolin; error bar: standard deviation. in each group.