Effects of BSF on Podocyte Apoptosis via Regulating the ROS-Mediated PI3K/AKT Pathway in DN

Figure 4

Effects of BSF on Bax, Bcl-2, caspase-9, and caspase-3 expressions in DN mice and HG-cultured podocytes. (a) Representative Bax, Bcl-2, caspase-9, and caspase-3 protein bands in the renal cortex from mice in different groups. (b) Comparison of Bax protein in the mouse renal cortex (). (c) Comparison of Bcl-2 protein in the mouse renal cortex (). (d) Comparison of caspase-9 protein in the mouse renal cortex (). (e) Comparison of caspase-3 protein in the mouse renal cortex (). (f) Representative Bax, Bcl-2, caspase-9, and caspase-3 protein bands in cultured podocytes in different groups. (g) Comparison of Bax protein in cultured podocytes (). (h) Comparison of Bcl-2 protein in cultured podocytes (). (i) Comparison of caspase-9 protein in cultured podocytes (). (j) Comparison of caspase-3 protein in cultured podocytes (). (k) Representative photograph of caspase-9 and caspase-3 staining in cultured podocytes. (l) Comparison of Bax mRNA levels in the rat renal cortex (). (m) Comparison of Bcl-2 mRNA levels in the rat renal cortex (). (n) Comparison Bax mRNA levels in cultured podocytes (). (o) Comparison of Bcl-2 mRNA levels in cultured podocytes ().

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