Serum 1,5-Anhydroglucitol to Glycated Albumin Ratio Can Help Early Distinguish Fulminant Type 1 Diabetes Mellitus from Newly Onset Type 1A Diabetes Mellitus

Figure 3

Strategies for application of glycemic indicators to differentiate FT1DM from T1ADM. (a) Differentiating FT1DM from T1ADM based on AGI only: to diagnose FT1DM and to diagnose T1ADM can successfully distinguish 53.73% of participants if they all have , with suspected FT1DM narrowed down by 26.87%. (b) FT1DM was distinguished from T1DM (both FT1DM and T1ADM) with HbA_1c less than 8.7% based on the combined criteria of AGI and HbA_1c: and diagnosed FT1DM; otherwise, T1ADM. The identifying success rate became 86.57% under the combined criteria, increasing by 61.11% in comparison with the use of the AGI criterion only. Abbreviations: 1,5-AG: 1,5-anhydroglucitol; AGI: 1,5-AG/GA index; FT1DM: fulminant type 1 diabetes mellitus; GA: glycated albumin; HbA_1c: glycated hemoglobin A_1c; T1ADM: type 1A diabetes mellitus; T1DM: type 1 diabetes mellitus (including FT1DM and T1ADM).

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