High Body Mass Index and Triglycerides Help Protect against Osteoporosis in Patients with Type 2 Diabetes Mellitus

Table 1

Clinical characteristics of patients with T2DM by BMI category.

	Normal weight group; (20–24.9 kg/m^2)	Overweight/obese group; (≥25 kg/m^2)	value
	29	50
Sex (F, %)	25 (51.7%)	20 (40%)	0.312
Age (years)			0.019
DM course (years)
0-1	7 (24.1%)	13 (26.0%)
1-10	14 (48.3%)	21 (42.0%)	0.858
>10	8 (27.6%)	16 (32.0%)
History of DM	10 (34.5%)	16 (32.0%)	0.821
Hypertension	11 (37.9%)	25 (50.0%)	0.299
Gastrointestinal disorders	4 (13.8%)	6 (12.0%)	1.000
Smoking	7 (24.1%)	19 (38.0%)	0.206
Drinking	6 (20.7%)	19 (38.0%)	0.111
HbA1c (%)	9.6 (4.2)	9.0 (2.4)	0.376
TC (mmol/L)			0.268
TG (mmol/L)	1.41 (1.01)	1.59 (1.18)	0.095
HDL-C (mmol/L)			0.031
LDL-C (mmol/L)			0.303
VLDL-C (mmol/L)	0.46 (0.22)	0.47 (0.38)	0.508
ApoA1 (mmol/L)			0.294
ApoB (mmol/L)			0.831
Total protein (g/L)			0.743
Albumin (g/L)			0.749
BUN (mmol/L)			0.442
Cr (μmmol/L)			0.180
25OHD (ng/mL)	13.18 (9.81)	15.25 (9.92)	0.248
OC (ng/mL)			0.421
β-CTX (ng/mL)	0.40 (0.29)	0.38 (0.33)	0.827
P1NP (ng/mL)	38.77 (17.46)	42.76 (29.99)	0.935
PTH (pg/mL)			0.915
OP	20 (69.0%)	15 (30.0%)	0.001

Note: data were expressed as number (%) or (interquartile range). Abbreviations: ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; BMD: bone mineral density; BMI: body mass index; BUN: blood urea nitrogen; Cr: creatinine; DM: diabetes mellitus; HbA1c: glycated hemoglobin; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; T2DM: type 2 diabetes mellitus; TC: total cholesterol; TG: triglyceride; VLDL-C: very-low-density lipoprotein cholesterol; OC: osteocalcin; OP: osteoporosis; P1NP: procollagen type 1 N-terminal propeptide; PTH: parathyroid hormone; 25OHD: 25-hydroxyvitamin D; β-CTX: β-C-terminal cross-linked telopeptide of type I collagen.