Research Article

High Body Mass Index and Triglycerides Help Protect against Osteoporosis in Patients with Type 2 Diabetes Mellitus

Table 2

Clinical characteristics of patients with T2DM by TG category.

Normal TG group
(≤1.7 mmol/L)
Hypertriglyceridemic group (>1.7 mmol/L) value

4633
Gender (F, %)18 (39.1%)17 (51.5%)0.274
Age (years)0.914
DM course (years)
 0-114 (30.4%)6 (18.2%)
 1-1019 (41.3%)16 (48.5%)0.466
 >1013 (28.3%)11 (33.3)
History of DM14 (30.4%)12 (36.4%)0.580
Hypertension16 (34.8%)20 (60.6%)0.023
Gastrointestinal disorders5 (10.9%)5 (15.2%)0.734
Smoking14 (30.4%)12 (36.4%)0.580
Drinking14 (30.4%)11 (33.3%)0.785
BMI (kg/m2)0.017
HbA1c (%)0.801
TC (mmol/L)0.014
HDL-C (mmol/L)0.321
LDL-C (mmol/L)0.015
VLDL-C (mmol/L)0.39 (0.24)0.65 (0.43)0.000
ApoA1 (mmol/L)0.158
ApoB (mmol/L)0.002
Total protein (g/L)0.056
Albumin (g/L)0.877
BUN (mmol/L)0.158
Cr (μmmol/L)0.682
25OHD (ng/mL)16.73 (9.72)13.61 (7.01)0.120
OC (ng/mL)0.020
β-CTX (ng/mL)0.49 (0.32)0.32 (0.24)0.007
P1NP (ng/mL)47.32 (25.95)34.79 (20.77)0.007
PTH (pg/mL)0.714
OP26 (56.5%)9 (27.3%)0.010

Note: data were expressed as number (%) or (interquartile range). Abbreviations: ApoA1: apolipoprotein A1; ApoB: apolipoprotein B; BMD: bone mineral density; BMI: body mass index; BUN: blood urea nitrogen; Cr: creatinine; DM: diabetes mellitus; HbA1c: glycated hemoglobin; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; T2DM: type 2 diabetes mellitus; TC: total cholesterol; TG: triglyceride; VLDL-C: very-low-density lipoprotein cholesterol; OC: osteocalcin; OP: osteoporosis; P1NP: procollagen type 1 N-terminal propeptide; PTH: parathyroid hormone; 25OHD: 25-hydroxyvitamin D; β-CTX: β-C-terminal cross-linked telopeptide of type I collagen.