Effects of Sodium-Glucose Cotransporter 2 Inhibition on Glucose Metabolism, Liver Function, Ascites, and Hemodynamics in a Mouse Model of Nonalcoholic Steatohepatitis and Type 2 Diabetes

Figure 5

Dapagliflozin does not affect plasma catecholamine concentrations or the renin-aldosterone system (RAS). Plasma catecholamine (adrenaline (a), noradrenaline (b), and dopamine (c)) (closed bar) and RAS factor (renin (d) and aldosterone (e)) (hatched bar) concentrations before (open bar) and 5 hours after each treatment. for each treatment group. vs. with PBS- or dapagliflozin-treated mice. ^†vs. PBS-treated mice. ^§vs. PBS- or dapagliflozin-treated mice. ^¶vs. PBS- and vs. dapagliflozin-treated mice. ^#vs. NCD-fed mice before each treatment.

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