Association between Admission Hyperglycemia and Culprit Lesion Characteristics in Nondiabetic Patients with Acute Myocardial Infarction: An Intravascular Optical Coherence Tomography Study

Table 1

Baseline characteristics of the study population.

	Non-DM by A/C tertiles					DM
		<1.08	1.08-1.22	>1.22
Age					0.438		0.725
BMI (kg/m^2)					0.467		0.038
Men	150 (82.4)	53 (88.3)	49 (79.0)	48 (80.0)	0.232	77 (81.1)	0.779
Smoking	125 (68.7)	46 (76.7)	42 (67.7)	37 (61.7)	0.077	67 (70.5)	0.752
Time from symptom onset (hour)	6.1 (2.9, 13.8)	7.3 (3.8, 14.7)	7.9 (3.3, 16.9)	3.7 (2.3, 8.0)	0.005	5.3 (2.7, 11.5)	0.576
Hypertension	101 (55.5)	36 (60.0)	31 (50.0)	34 (56.7)	0.714	61 (64.2)	0.162
Dyslipidemia	166 (91.2)	54 (90.0)	55 (88.7)	57 (95.0)	0.335	85 (89.5)	0.638
Prior PCI	12 (6.6)	3 (5.0)	5 (8.1)	4 (6.7)	0.714	9 (9.5)	0.390
ABG (mg/dl)	132.6 (119.5, 146.3)	116.4 (108.5, 124.3)	133.5 (126.1, 142.0)	154.6 (139.0, 177.2)	<0.001	211.5 (177.2, 271.3)	<0.001
HbA1c (%)	5.7 (5.5, 5.9)	5.8 (5.6, 6.0)	5.7 (5.5, 5.9)	5.6 (5.4, 5.8)	<0.001	7.9 (7.0, 9.3)	<0.001
A/C	1.15 (1.03, 1.27)	0.97 (0.92, 1.03)	1.15 (1.10, 1.18)	1.34 (1.27, 1.46)	<0.001	1.21 (1.03, 1.38)	0.127
cTnI					0.009		0.583
CK-MB					0.038		0.200
WBC (10^6/l)					0.082		0.995
Hb (g/l)					0.993		0.331
TC (mg/dl)					0.858		0.108
TG (mg/dl)					0.988		<0.001
HDL-C (mg/dl)					0.074		0.189
LDL-C (mg/dl)					0.888		0.327
Lp(a) (mg/l)					0.130	130.2 (54.5, 309.8)	0.070
eGFR (mL/min/1.73 m^2)					0.183		0.211
Hs-CRP (mg/l)	5.3 (2.5, 10.9)	5.6 (2.9, 11.1)	5.9 (2.8, 10.4)	4.6 (1.8, 11.0)	0.337	6.4 (2.7, 10.3)	0.748
LVEF (%)					0.092		0.208
Aspirin	63 (34.6)	25 (41.7)	19 (30.6)	19 (31.7)	0.251	41 (43.2)	0.163
P2Y12 inhibitor	42 (23.1)	17 (28.3)	15 (24.2)	10 (16.7)	0.130	28 (29.5)	0.245
Statin	34 (18.7)	11 (18.3)	12 (19.4)	11 (18.3)	1.000	13 (13.7)	0.293
Culprit vessels					0.240		0.245
LAD	88 (48.4)	28 (46.7)	26 (41.9)	34 (56.7)		47 (49.5)
LCX	23 (12.6)	5 (8.3)	13 (21.0)	5 (8.3)		6 (6.3)
RCA	71 (39.0)	27 (45.0)	23 (37.1)	21 (35.0)		42 (44.2)
LM disease	5 (2.7)	3 (5.0)	1 (1.6)	1 (1.7)	0.265	1 (1.1)	0.358
MVD	127 (69.8)	43 (71.7)	41 (66.1)	43 (71.7)	1.000	77 (81.1)	0.043
Pre-TIMI flow					0.763		0.480
0	124 (68.1)	39 (65.0)	43 (69.4)	42 (70.0)		56 (58.9)
1	9 (4.9)	4 (6.7)	3 (4.8)	2 (3.3)		5 (5.3)
2	15 (8.2)	6 (10.0)	4 (4.8)	5 (8.3)		10 (10.5)
3	34 (18.7)	11 (18.3)	12 (19.4)	11 (18.3)		24 (25.3)
Aspiration	107 (58.8)	35 (58.3)	37 (59.7)	35 (58.3)	1.000	65 (68.4)	0.117
Predilation	148 (81.3)	48 (80.0)	50 (80.6)	50 (83.3)	0.640	72 (75.8)	0.280

Data shown are number (%), median (25th, 75th percentiles), or . ABG: acute blood glucose; A/C: acute-to-chronic glycemic ratio; BMI: body mass index; CK-MB: creatine kinase MB; cTnI: cardiac troponin I; DM: diabetes mellitus; eGFR: estimated glomerular filtration rate; HbA1c: glycosylated hemoglobin; HDL-C: high-density lipoprotein cholesterol; Hs-CRP: high-sensitivity C-reactive protein; LAD: left anterior descending artery; LCX: left circumflex artery; LM: left main coronary artery; LVEF: left ventricular ejection fraction; MVD: multivessel disease; non-DM: patients without diabetes mellitus; PCI: percutaneous coronary intervention; RCA: right coronary artery; TC: total cholesterol; TG: triglyceride; TIMI: thrombolysis in myocardial infarction; WBC; white blood cell.