A Comparison of the Association of Fasting Plasma Glucose and HbA1c Levels with Diabetic Retinopathy in Japanese Men
Table 1
Comparison of the clinical characteristics of the subjects in the FPG and HbA1c groups ().
FPG
Number with retinopathy/total
Systolic blood pressure (mmHg)
Diastolic blood pressure (mmHg)
BMI (kg/m2)
Mean
SE
value
Mean
SE
value
Mean
SE
value
Group 1
≤94 mg/dl
6/540 (1.1%)
119.1
(0.5)
Ref.
76.4
(0.3)
Ref.
22.9
(0.1)
Ref.
Group 2
95-99 mg/dl
5/595 (0.8%)
121.0
(0.5)
0.006
78.2
(0.3)
0.0003
23.6
(0.1)
<0.0001
Group 3
100-104 mg/dl
6/574 (1.0%)
121.9
(0.5)
0.0001
77.9
(0.3)
0.003
24.1
(0.1)
<0.0001
Group 4
105-109 mg/dl
6/399 (1.5%)
123.7
(0.6)
<0.0001
79.4
(0.4)
<0.0001
24.2
(0.1)
<0.0001
Group 5
110-117 mg/dl
7/381 (1.8%)
125.4
(0.6)
<0.0001
80.1
(0.4)
<0.0001
24.6
(0.1)
<0.0001
Group 6
118-125 mg/dl
5/161 (3.1%)
126.1
(0.6)
<0.0001
80.5
(0.6)
<0.0001
25.2
(0.2)
<0.0001
Group 7
126-144 mg/dl
8/154 (5.2%)
123.9
(0.9)
<0.0001
78.7
(0.6)
0.003
24.9
(0.2)
<0.0001
Group 8
≥145 mg/dl
6/117 (5.1%)
125.8
(1.0)
<0.0001
78.5
(0.7)
0.006
24.7
(0.2)
<0.0001
HbA1c
Number with retinopathy/total
Systolic blood pressure (mmHg)
Diastolic blood pressure (mmHg)
BMI (kg/m2)
Mean
SE
value
Mean
SE
value
Mean
SE
value
Group 1
≤5.5%
6/657 (0.9%)
122.9
(0.5)
Ref.
79.1
(0.3)
Ref.
23.1
(0.1)
Ref.
Group 2
5.6-5.7%
6/708 (0.8%)
121.2
(0.5)
0.091
77.7
(0.3)
0.005
23.6
(0.1)
0.001
Group 3
5.8-5.9%
8/629 (1.3%)
122.1
(0.5)
1.0
78.5
(0.3)
0.67
24.1
(0.1)
<0.0001
Group 4
6.0-6.1%
6/372 (1.6%)
122.3
(0.6)
1.0
78.2
(0.4)
0.34
24.5
(0.1)
<0.0001
Group 5
6.2-6.3%
4/192 (2.1%)
124.1
(0.9)
1.0
78.8
(0.6)
1.0
25.1
(0.2)
<0.0001
Group 6
6.4-6.5%
3/101 (3.0%)
124.0
(1.2)
1.0
78.6
(0.8)
1.0
24.6
(0.3)
<0.0001
Group 7
6.6-6.7%
2/49 (4.1%)
122.8
(1.7)
1.0
78.7
(1.1)
1.0
25.3
(0.4)
<0.0001
Group 8
≥6.8%
14/213 (6.6%)
123.4
(0.8)
1.0
77.8
(0.5)
0.18
24.8
(0.2)
<0.0001
Mean and standard error (SE) were adjusted for age by analysis of covariance (ANCOVA). values were for comparisons between Group 1 and other groups and adjusted for multiplicity (7 comparisons) using Bonferroni-Holm’s method.