Association between Circulating B-Type Natriuretic Peptide and Diabetic Peripheral Neuropathy: A Cross-Sectional Study of a Chinese Type 2 Diabetic Population
Table 3
Binary logistic regression analyses of variables contributing to DPN in patients with T2DM.
Variables
Univariate analysis
Multivariate analysis
OR (95% CI)
value
OR (95% CI)
value
Sex
-0.478
0.620 (0.345-1.114)
0.110
Age
0.035
1.036 (1.007-1.066)
0.016
BMI
-0.155
0.856 (0.784-0.935)
0.001
Diabetes duration
0.043
1.044 (1.003-1.088)
0.037
SBP
-0.005
0.995 (0.983-1.007)
0.445
DBP
-0.006
0.994 (0.973-1.017)
0.614
FBG
0.058
1.059 (1.008-1.113)
0.022
HbA1c
0.118
1.125 (1.009-1.254)
0.033
0.441
1.554 (1.015-2.378)
0.042
TC
-0.167
0.846 (0.646-1.107)
0.223
TG
-0.082
0.921 (0.765-1.109)
0.387
HDL-C
0.474
1.607 (0.685-3.767)
0.275
LDL-C
-0.163
0.849 (0.604-1.194)
0.348
Neutrophil count
0.211
1.235 (1.055-1.446)
0.009
Lymphocyte count
-1.221
0.295 (0.157-0.555)
<0.001
NLR
0.228
1.257 (1.112-1.419)
<0.001
WBC count
0.051
1.053 (0.901-1.230)
0.516
PT
0.182
1.200 (0.827-1.740)
0.337
APTT
0.055
1.056 (0.986-1.132)
0.120
INR
0.870
2.387 (0.020-287.730)
0.722
Fibrinogen
0.404
1.498 (1.108-2.026)
0.009
BNP
0.020
1.020 (1.006-1.034)
0.004
0.043
1.044 (1.006-1.084)
0.024
ACR
0.000
1.000 (1.000-1.001)
0.112
Creatinine
0.016
1.016 (1.005-1.026)
0.003
eGFR
-0.020
0.981 (0.969-0.993)
0.002
DR
0.820
2.270 (1.060-4.862)
0.035
DFU
1.570
4.805 (1.597-14.455)
0.005
PAD
1.153
3.167 (1.571-6.386)
0.001
CHD
0.534
1.705 (0.818-3.557)
0.155
Stroke
0.499
1.648 (0.878-3.093)
0.120
Beta is the standardized coefficient and measures the influence of each variable on DPN; OR is the odds ratio and refers to the risk of DPN.
