The Effects of New Selective PPARα Agonist CP775146 on Systematic Lipid Metabolism in Obese Mice and Its Potential Mechanism

Figure 4

CP775146 activates PPARα-mediated gene expression in the eWAT of mice fed an HFD. eWAT H&E staining data,  μm; /group. (a) Chow-fed group, (b) HFD-NC group, (c) HFD-CP775146 0.1 mg/kg group, and (d) HFD-CP775146 0.3 mg/kg group. (e) The expression levels of genes involved in thermogenesis and lipolysis. are shown (/group). , , and vs. the chow-fed group; ^#, ^##, and ^### vs. HFD-NC group.

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