Research Article

The Effect of Prior Gestational Diabetes on the Shape of the Glucose Response Curve during an Oral Glucose Tolerance Test 3 Years after Delivery

Table 2

Characteristics of participants by glucose curve phenotype.

Shape of glucose curveBiphasicMonophasic

Age at follow-up (year)0.04
Follow-up (year)0.96
Weight (kg)0.1
BMI (kg/m2)0.15
Waist circumference (cm)0.14
Waist-to-hip ratio0.78
Smoking, (%)12 (27.3)15 (18.8)0.36
Number of previous pregnancies, (%)0.06
 None21 (48.8)24 (30.4)
 One11 (25.6)26 (32.9)
 More than one11 (25.6)29 (36.7)
Early GDM, (%)11 (23.4)36 (45.0)0.034
Fasting glucose (mmol/l)0.26
2-hour glucose (mmol/l)0.873
Glucose intolerance, (%)6 (14)18 (23)0.34
A1C (%)0.46
AUCglu (mmol/lmin)753 [129]897 [310]0.009
Fasting insulin (μU/ml)8.47 [4.38]9.07 [9.83]0.66
HOMA2-S90.0 [44.7]82.2 [89.4]0.82
HOMA2-B98.0 [44.9]91.3 [56.1]0.90
HDL cholesterol (mmol/l)0.21
LDL cholesterol (mmol/l)0.44
Serum triglyceride (mmol/l)0.9 [0.8]1.0 [1.0]0.033
Systolic blood pressure (mmHg)0.06
Diastolic blood pressure (mmHg)0.17
Hypertension, (%)5 (12)16 (20)0.32
C-reactive protein (mg/l)1.1 [2.05]1.1 [2.95]0.25

or  = median [IQR].