Qualitative and Quantitative Analysis of B-Cell-Produced Antibodies in Vitreous Humor of Type 2 Diabetic Patients with Diabetic Retinopathy

Table 3

Correlations between clinical characteristics, serum metrics, and levels of antibodies.

Clinical characteristics	IgA (ng/ml)		IgM (ng/ml)		Antibodies (ng/ml)
	value	value	value	value	value	value
Age (y)	-0.186	0.029	-0.123	0.108	-0.097	0.164
Sex	0.119	0.114	-0.082	0.204	-0.053	0.298
Duration of DM (years)	0.128	0.099	0.260	0.004	0.146	0.070
Duration of DR (months)	0.178	0.036	0.069	0.242	0.026	0.395
SBP (mmHg)	0.121	0.110	-0.027	0.392	-0.005	0.480
DBP (mmHg)	0.203	0.020	0.027	0.393	-0.008	0.468
FBG (mmol/l)	0.317	0.001	0.132	0.091	-0.005	0.479
HbA1c (%)	0.296	0.001	0.276	0.002	0.201	0.020
sCr (μmol/l)	0.276	0.002	0.147	0.068	0.094	0.171
BUN (mmol/l)	0.287	0.002	0.14	0.078	0.119	0.115
eGFR (ml/min/1.73 m^2)	-0.443	<0.001	-0.377	<0.001	-0.289	0.001
UACR (mg/g)	0.110	0.133	0.363	<0.001	0.185	0.030

Abbreviation: DM: diabetes mellitus; Ig: immunoglobulin; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBG: fasting blood glucose; HbA1c: glycated hemoglobin; sCr: serum creatinine; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; UACR: urinary albumin to creatinine ratio. Italicized letters: low correlations were found between B-cell-produced antibodies and clinical variables of DM. Statistically significant value of <0.05 by Pearson’s correlation analysis. Statistically significant value of <0.001 by Pearson’s correlation analysis.