Renal Biomarkers for Treatment Effect of Ranibizumab for Diabetic Macular Edema

Table 4

Correlation between estimated glomerular filtration rate and changes in visual acuity and optical coherence tomography characteristics after Month 12 after ranibizumab treatment.

	Correlation coefficient or odds ratio				value
Changes at month 12	A: eGFR >90 ()	B: eGFR 61-90 ()	C: eGFR 30-60 ()	D: eGFR <30 ()	A vs. B	A vs. C	A vs. D
LogMAR of BCVA	Reference	0.115	-0.04	0.23	0.19	0.67	0.040
CFT (μm)	Reference	-29	-50	-58	0.31	0.080	0.056
Intraretinal cysts	Reference	1.10	2..81	3.88	0.91	0.20	0.11
Subretinal fluid	Reference

CFT: central foveal thickness; eGFR: estimated glomerular filtration rate; LogMAR of BCVA: logarithm of the minimum angle of resolution of best-corrected visual acuity.