Clinical Study

Simultaneous Pancreas Kidney Transplantation Improves Cardiovascular Autonomic Neuropathy with Improved Valsalva Ratio as the Most Precocious Test

Table 2

Results of cardiovascular autonomic tests, comparing evolution before and after SPK transplantation in paired patient samples. Statistically results () are marked in bold.

TestComparison periodsStatisticsCorrelationsTest
MeanStandard Deviat.Mean typical errorCorrelationSig.Sig. (bilateral)

SBPBefore SPK17-23.7617.444.230.110.68-1.130.28
3rd year-18.0013.833.35
Before SPK16-24.6217.324.330.520.04-2.360.03
5th-6th year-15.6612.813.20
Before SPK4-13.508.854.42-0.890.110.450.69
7th-8th year-20.5023.2711.64
Before SPK3-31.3334.4319.89-0.890.30-0.710.55
9th-10th year0.3345.2826.14

Valsalva ratioBefore SPK171.110.120.030.490.05-3.460.00
3rd year1.210.130.03
Before SPK171.090.070.020.520.03-5.390.00
5th-6th year1.230.130.03
Before SPK51.120.080.040.920.03-2.410.07
7th-8th year1.290.230.10
Before SPK31.130.110.060.870.33-2.790.11
9th-10th year1.360.220.13

30 : 15 ratioBefore SPK161.020.030.010.350.18-1.830.09
3rd year1.050.060.02
Before SPK161.030.050.010.050.85-1.720.11
5th-6th year1.100.150.04
Before SPK51.010.020.01-0.720.17-0.780.48
7th-8th year1.050.080.03
Before SPK30.990.010.00-0.840.36-1.340.31
9th-10th year1.110.150.09

/ ratioBefore SPK111.100.080.020.770.00-1.980.08
3rd year1.050.060.02
Before SPK121.080.070.020.700.01-1.200.26
5th-6th year1.110.110.03
Before SPK21.060.030.021.000.000.520.69
7th-8th year1.060.020.01

SBP: systolic blood pressure response to orthostasis; 30 : 15 ratio: heart rate response to orthostasis; / ratio: expiration/inspiration or deep breathing ratio; SPK: simultaneous pancreas kidney transplantation.