Research Article

Neonatal Hypoglycemia Related to Glycine Levels in Uncontrolled Gestational Diabetes Mellitus during Mid-Late Pregnancy: Multicenter, Prospective Case-Cohort Observational Study

Table 1

Characteristics and outcomes of the study population.

GDMControlχ2

11166173
Maternal age (years)<0.001
Gestational weeks (days)<0.001
Body mass index (kg/m2)
 Prepregnancy0.723
 Antepartum<0.001
Mode of delivery, no. (%)5.9740.113
 Spontaneous vaginal722 (64.7)4074 (66.0)
 Assisted vaginal93 (8.3)395 (6.4)
 Elective cesarean172 (15.4)944 (15.3)
 Emergency cesarean129 (11.6)760 (12.3)
Neonatal outcomes
Gender, no. (%)0.0080.931
 Male581 (52.1)3205 (51.9)
 Female535 (47.9)2968 (48.1)
Birth weight (g)0.004
Hypoglycemia, no. (%)145 (13.4)123 (2.0)322.926<0.001
Premature, no. (%)166 (14.9)362 (5.7)114.199<0.001
Meconium-stained amniotic fluid, no. (%)5.6770.128
 Clear812 (72.8)4432 (71.8)
 I218 (19.5)1346 (21.8)
 II65 (5.8)315 (5.1)
 III21 (1.9)80 (1.3)
Bad outcomes after delivery, no. (%)
at 1 min36 (3.2)278 (4.5)3.7430.053
at 5 min7 (0.6)48 (0.8)0.2850.593
at 10 min7 (0.6)40 (0.6)0.0060.936
Admission to intensive care unit9 (0.8)56 (0.9)0.1080.742

Data given as the or no. (%). GDM: gestational diabetes mellitus; BMI: body mass index.