Research Article

Abnormal Peripheral Neutrophil Transcriptome in Newly Diagnosed Type 2 Diabetes Patients

Table 3

Clinical and biochemical characteristics of the study participants for validation.

HC ()T2D () value

Sex (male/female)8 (6/2)8 (6/2)1.000
Age (years)0.496
BMI (kg/m2)0.273
WHR0.388
DBP (mmHg)0.316
SBP (mmHg)0.733
TG (mmol/L)0.903
TC (mmol/L)a4.77 (4.05~4.93)3.96 (2.50~4.56)0.050
HDL-C (mmol/L)0.332
LDL-C (mmol/L)0.065
HbA1c (%)a5.30 (5.20~5.55)6.50 (6.05~7.70)<0.001
Fasting BS (mmol/L)a4.61 (4.21~5.11)5.97 (5.14~7.65)0.002
2 h postprandial BS (mmol/L)<0.001
Fasting C-peptide (pmol/L)0.420
2 h postprandial C-peptide (pmol/L)0.264
White cell count (109/L)0.411
Lymphoid cell count (109/L)0.695
Neutrophil count (109/L)a3.41 (3.12~3.50)3.42 (2.88~3.68)0.878
Mononuclear count (109/L)0.095

Data are expressed by or median (25-75th percentile). BMI: body mass index; WHR: waist to hip ratio; DBP: diastolic blood pressure; SBP: systolic blood pressure; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; acompared by the Mann-Whitney test. compared with HC. compared with HC. compared with HC.