Journal of Diabetes Research

Research Article

Choroidal Vascularity Index as a Biomarker for Visual Response to Antivascular Endothelial Growth Factor Treatment in Diabetic Macular Edema

Table 2

Baseline optical coherence tomography morphological feature comparison between responders and nonresponders by a generalized estimating equation model with adjusting for correlation between two eyes within the same patient ( eyes).


	Responders ()	Nonresponders ()

LCA (mm²)			0.059
TCA (mm²)			0.168
SFCT (μm)			0.145
CVI			0.014
Reflectivity of EZ			0.030
Reflectivity of ELM			0.538
Reflectivity of RPE			0.243
Adjusted reflectivity of EZ			0.006
Adjusted reflectivity of ELM			0.335
Disruption of the EZ (μm)			0.168
Disruption of the ELM (μm)			0.421
DRIL, (%)	8 (16.0)	20 (47.6)	0.001
SRF, (%)	26 (52.0)	16 (38.1)	0.038
Cystoid abnormalities, (%)	39 (78.0)	33 (78.6)	0.987
Epiretinal membrane, (%)	16 (32.0)	13 (31.0)	0.640
HRF			0.563

LCA: luminal choroidal area; TCA: total choroidal area; SFCT: subfoveal choroidal thickness; CVI: choroidal vascularity index; EZ: ellipsoid zone; ELM: external limiting membrane; RPE: retinal pigment epithelium; DRIL: disorganization of the retinal inner layers; SRF: subretinal fluid; HRF: hyperreflective foci.