Elevated Anthropometric and Metabolic Indicators among Young Adult Offspring of Mothers with Pregestational Diabetes: Early Results from the Transgenerational Effect on Adult Morbidity Study (the TEAM Study)

Table 1

The TEAM Study visit procedures, methods, lab tests, and assessments.

Assessment	Measurement
Pregnancy test	Urine pregnancy testing (for females)
Questionnaires	Health history, sociodemographic, physical activity, and sleep questionnaires
Cardiovascular	Endothelial & vascular function (Endo-Pat, FMD), blood pressure, brachial artery distensibility, augmentation index (AiX) and pulse wave velocity (PWV), carotid ultrasound, echocardiography
Renal	Creatinine, cystatin C, albumin, hepatic panel
Metabolic, diabetogenic	Oral glucose tolerance test (glucose, insulin), glucose-like peptide 1 (GLP-1), gastric inhibitory polypeptide (GIP), glucagon, C-peptide, hemoglobin A1c (HbA1C), lipids, islet cell antibodies (ICA), adiponectin, leptin, phospholipids, free fatty acids, high-sensitivity C-reactive protein (hsCRP), vitamin D, thyroid-stimulating hormone (TSH)
Nutrition	24-hour food recall (followed by 2 postvisit recalls) & block food frequency V3
Anthropometric	Hip, waist (iliac and midpoint) and sagittal abdominal diameter (SAD), dual X-ray absorptiometry (DXA)
Neurocognitive	Brief Symptom Index (BSI-18); Conners’ Adult ADHD Ratings Scale (CAARS); Wechsler Abbreviated Scale of Intelligence, 2^nd edition (WASI-II); Social Responsiveness Scale (SRS-2); PedsQL