Research Article

Elevated Anthropometric and Metabolic Indicators among Young Adult Offspring of Mothers with Pregestational Diabetes: Early Results from the Transgenerational Effect on Adult Morbidity Study (the TEAM Study)

Table 2

Demographic and glycemic measures comparing TEAM participants to NHANES participants matched on age, race, and sex.

NHANES participants ()TEAM participants () value

Age
 Mean (standard deviation)31.8 (5.0)32.0 (4.5)0.78
 Median (25th–75th percentile)32.0 (28.0-36.0)32.2 (28.0-35.5)
Race
 White175 (82.2)85 (88.5)0.16
 Black38 (17.8)11 (11.5)
Male sex118 (55.4)52 (54.2)0.84
BMI (kg/m2)
 Mean (standard deviation)29.1 (7.5)31.8 (8.1)0.01
 Median (25th–75th percentile)27.4 (23.8-33.0)30.4 (26.4-35.1)
 Normal68 (31.9)20 (20.8)0.04
 Overweight68 (31.9)24 (25.0)
 Class I obesity39 (18.3)28 (29.2)
 Class II obesity19 (8.9)10 (10.3)
 Class III obesity19 (8.9)14 (14.6)
Iliac waist circumference (cm)
 Mean (standard deviation)98.3 (17.8)102.2 (18.6)0.09
 Median (25th–75th percentile)95.9 (85.5-108.5)98.7 (88.8-112.1)
Systolic blood pressure (mmHg)
 Mean (standard deviation)117.6 (12.4)119.6 (11.5)0.18
 Median (25th–75th percentile)116.0 (109.3-124.7)117.2 (111.8-126.2)
Diastolic blood pressure (mmHg)
 Mean69.4 (9.3)75.2 (10.6)<0.0001
 Median69.3 (62.7-76.0)74.0 (68.0-83.0)
Fasting glucose (mg/dL)
 Mean (standard deviation)100.6 (23.9)90.8 (23.0)0.001
 Median (25th–75th percentile)98.0 (92.0-103.0)85.7 (80.2-96.2)
 <100121 (56.8)79 (82.3)<0.0001
 100-<12686 (40.4)13 (13.5)
 ≥1266 (2.8)4 (4.2)
Two-hour glucose (mg/dL)
 Mean (standard deviation)100.8 (37.9)133.5 (49.2)<0.0001
 Median (25th–75th percentile)95.0 (82.5-116.0)124.3 (102.3-144.8)
 <140171 (92.9)69 (71.9)<0.0001
 140-<20010 (5.4)21 (21.9)
 ≥2003 (1.6)6 (6.3)
HbA1C (%)
 Mean (standard deviation)5.3 (0.8)5.4 (0.8)0.24
 Median (25th–75th percentile)5.2 (5.0-5.5)5.3 (5.1-5.6)
 <5.7%188 (88.7)80 (83.3)0.34
 5.7-6.4%20 (9.4)12 (37.5)
 ≥6.5%4 (1.9)4 (4.2)

For continuous variables, difference between means and for categorical variables, chi-square.