Characterizing Glycemic Control and Sleep in Adults with Long-Standing Type 1 Diabetes and Hypoglycemia Unawareness Initiating Hybrid Closed Loop Insulin Delivery
Table 1
BMI and glycemic characteristics at baseline and at 3 months, 6 months, and 9 months after initiating hybrid closed loop insulin delivery and the change values from baseline to 9 months in BMI and glycemic characteristics.
Variable
Baseline Mean (SD)
3 months Mean (SD)
6 months Mean (SD)
9 months Mean (SD)
-test
Effect sizea
Baseline to 9 months
BMI
24.18 (1.12)
24.54 (1.63)
23.73 (1.41)
24.51 (1.36)
-0.78
0.47
0.26
HbA1c (%)
7.25 (1.33)
7.48 (0.56)
7.60 (1.03)
7.48 (1.06)
-0.64
0.55
0.19
Mean sensor glucose (mg/dL)
147.83 (24.32)
156.33 (23.75)
154.50 (28.56)
153.67 (32.50)
-0.61
0.57
0.20
Percentage of time sensor glucose was in range
70-180 mg/dL
66.60 (12.80)
68.00 (15.02)
68.40 (21.34)
70.00 (23.48)
-0.43
0.69
0.28
Percentage of time sensor glucose was below and above range (total)
<54 mg/dL
1.50 (1.93)
0.86 (0.87)
0.37 (0.28)
0.51 (0.68)
1.21
0.28
0.68
<60 mg/dL
2.35 (2.83)
1.38 (1.32)
0.72 (0.33)
0.88 (0.91)
1.32
0.24
0.70
<70 mg/dL
4.86 (5.34)
2.54 (2.00)
2.01 (0.84)
2.22 (1.42)
1.36
0.23
0.67
>180 mg/dL
25.63 (15.20)
27.57 (16.07)
27.88 (20.05)
26.41 (22.33)
-0.13
0.90
0.04
>250 mg/dL
4.66 (4.25)
7.29 (8.01)
6.54 (9.72)
7.58 (12.11)
-0.61
0.57
0.32
Percentage of time sensor glucose was below and above range during the daytime as defined by accelerometry estimated sleep-wake period
<54 mg/dL
1.25 (1.25)
1.15 (1.02)
0.49 (0.51)
0.67 (0.91)
0.99
0.37
0.52
<60 mg/dL
1.99 (2.05)
1.83 (1.59)
0.91 (0.58)
1.12 (1.22)
1.14
0.31
0.52
<70 mg/dL
4.27 (4.22)
3.37 (2.60)
2.40 (1.20)
2.70 (2.11)
1.21
0.28
0.47
>180 mg/dL
26.50 (17.72)
30.89 (15.15)
32.29 (17.38)
30.84 (22.26)
-1.11
0.32
0.22
>250 mg/dL
4.70 (4.32)
9.37 (9.55)
8.04 (10.37)
8.70 (13.52)
-0.91
0.40
0.40
Percentage of time sensor glucose was below and above range during the nighttime as defined by accelerometry estimated sleep-wake period
