miR-126 Mimic Counteracts the Increased Secretion of VEGF-A Induced by High Glucose in ARPE-19 Cells

Figure 4

Expression of PIK3R2 in ARPE-19 cells cultured for 24 hours in standard medium (CTR), silencing (INHIB) and upregulating (MIMIC) miR-126 in control condition and in presence of high glucose (HG). (a) PIK3R2 gene expression normalized vs. β-actin as housekeeping gene. Representative Western blot analysis of (b) PIK3R2 protein expression with quantification of densitometries of relative bands. Data were expressed as of fold induction relative to β-actin of three independent experiments (). , , and vs. CTR; ^§, ^§§, and ^§§§ HG+mimic vs. HG.

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