Low Molecular Weight Fucoidan Can Inhibit the Fibrosis of Diabetic Kidneys by Regulating the Kidney Lipid Metabolism

Figure 3

Assessment of lipid metabolism in rat kidneys. (a) Oil red O staining to observe lipid deposition in the kidneys of rats and Oil red O staining statistical analysis results. (b) Serum biochemical analysis: variations in TC, TG, LDL-C, and HDL-C at the end of the experiment ( vs. the Sham group; ## vs. the DKD group, ). Detection of (c) TC and (d) TG contents in the kidneys of rats ( vs. the Sham group; ## vs. the DKD group, ). (d) Variation of regulatory factor mRNA expressions. (e) Detection of regulatory factor protein expressions by western blot. (f) Statistical protein expressions of the regulatory factors of lipid metabolism (, vs. the Sham group; ## vs. the DKD group, ). The statistical results were compared with the Sham operation group and other groups.

(a)

(b)

(c)

(d)

(e)

(f)