Diastolic Cardiac Function Improvement by Liraglutide Is Mainly Body Weight Reduction Dependent but Independently Contributes to B-Type Natriuretic Peptide Reduction in Patients with Type 2 Diabetes with Preserved Ejection Fraction

Table 2

Comparison of clinical parameters at baseline and after 26 weeks of liraglutide treatment.

	Baseline	26 week	value
HbA1c (%)
Creatinine (mg/dL)			0.55
Systolic blood pressure (mmHg)			0.88
Diastolic blood pressure (mmHg)
Heart rate (bpm)			0.43
Body mass index (kg/m^2)
B-type natriuretic peptide (pg/mL)
Septal
Proportion of diastolic cardiac dysfunction	13 (42%)	9 (29%)	0.33
E/A ratio			0.46
Deceleration time (msec)			0.72
Left atrial diameter (mm)			0.48
Left ventricular diastolic diameter (mm)			0.12
Left ventricular ejection fraction (%)			0.43

Data are or (%) unless otherwise specified. : wave to ratio on tissue Doppler echocardiography; : ratio of transmitral wave velocity to transmitral wave ratio on transmitral flow image. .