Research Article

Serum Metabolites as an Indicator of Developing Gestational Diabetes Mellitus Later in the Pregnancy: A Prospective Cohort of a Chinese Population

Table 1

Baseline characteristics and clinical information in the case and control groups.

VariablesCase ()Control () value

Gestational age of investigation12.6 (±0.87)12.7 (±0.61)0.503
Gestational age of blood collection12.7 (±0.99)12.8 (±0.77)0.625
Maternal age (years)32.4 (±4.61)31.7 (±4.33)0.494
Early pregnancy weight (kg)57.7 (±9.27)51.1 (±7.24)<0.001
Early pregnancy BMI (kg/m2)23.4 (±3.23)20.4 (±2.49)<0.001
Early pregnancy SBP (mmHg)120.0 (±10.38)113.7 (±10.07)<0.001
Early pregnancy DBP (mmHg)77.0 (±8.55)72.2 (±7.90)<0.001
Gravidity2.5 (±1.22)2.3 (±1.46)0.608
Parity0.6 (±0.61)0.6 (±0.50)1.000
History of GDM0.010
 No43 (84.3%)51 (100.0%)
 Yes8 (15.7%)0 (0.0%)
History of gestational hypertension1.000
 No50 (98.0%)50 (98.0%)
 Yes1 (2.0%)1 (2.0%)
Smoking0.475
 No51 (100%)49 (96.1%)
 Yes0 (0%)2 (3.9%)
Drinking0.475
 No51 (100.0%)49 (96.1%)
 Yes0 (0%)2 (3.9%)
HGB (g/L)127.9 (±8.55)122.9 (±8.78)0.004
TG (mmol/L)1.8 (±0.68)1.5 (±0.72)0.067
TC (mmol/L)4.6 (±0.70)4.4 (±0.70)0.262
HDL (mmol/L)1.8 (±0.40)1.9 (±0.37)0.079
LDL (mmol/L)2.6 (±0.60)2.3 (±0.62)0.034

Data are (%), . BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HGB: hemoglobin; TG: triglyceride; TC: total cholesterol; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol.