Association between the Plasma-Glycosylated Hemoglobin A1c/High-Density Lipoprotein Cholesterol Ratio and Carotid Atherosclerosis: A Retrospective Study

Table 4

OR (95% CIs) of abnormal cIMT and carotid artery plaque by quartiles of the HbA1c/HDL-C ratio in patients without DM ().

	HbA1c/HDL-C
	Each 1-unit increase	Q1 (<4.41)	Q2 (4.41–5.23)	Q3 (5.23–6.38)	Q4 (>6.38)	for trend
Abnormal mean cIMT (≥1 mm)
Model 1^†	1.11 (1.02–1.22)	Ref.	1.27 (0.87–1.86)	1.16 (0.79–1.69)	1.67 (1.14–2.44)	0.020
Model 2^†	1.10 (1.00–1.22)	Ref.	1.24 (0.83–1.85)	1.25 (0.84–1.87)	1.61 (1.07–2.44)	0.032
Model 3^†	1.09 (0.99–1.20)	Ref.	1.24 (0.83–1.85)	1.22 (0.81–1.82)	1.56 (1.03–2.36)	0.052
Model 4^†	1.16 (1.05–1.29)	Ref.	2.02 (0.81–1.56)	1.54 (1.10–2.16)	2.02 (1.30–3.15)	0.002
Abnormal maximum cIMT (≥1 mm)
Model 1^†	1.13 (1.03–1.24)	Ref.	1.11 (0.76–1.62)	1.11 (0.76–1.62)	1.63 (1.10–2.40)	0.021
Model 2^†	1.13 (1.02–1.25)	Ref.	1.09 (0.73–1.62)	1.21 (0.81–1.81)	1.60 (1.06–2.44)	0.025
Model 3^†	1.11 (1.00–1.23)	Ref.	1.08 (0.72–1.61)	1.15 (0.77–1.73)	1.52 (1.00–2.32)	0.051
Model 4^†	1.18 (1.06–1.31)	Ref.	1.09 (0.73–1.65)	1.25 (0.83–1.90)	1.92 (1.23–2.99)	0.004
Carotid artery plaque
Model 1^†	1.20 (1.07–1.34)	Ref.	1.42 (0.93–2.16)	1.05 (0.70–1.58)	2.01 (1.29–3.14)	0.015
Model 2^†	1.22 (1.08–1.38)	Ref.	1.46 (0.94–2.28)	1.20 (0.78–1.86)	2.10 (1.29–3.40)	0.011
Model 3^†	1.20 (1.06–1.36)	Ref.	1.41 (0.89–2.21)	1.12 (0.72–1.74)	1.98 (1.21–3.25)	0.027
Model 4^†	1.25 (1.10–1.43)	Ref.	1.43 (0.90–2.27)	1.17 (0.74–1.83)	2.31 (1.39–3.86)	0.007