An <i>In Vitro</i> Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration

<div>A Matrigel-based tube formation assay to assess the vasogenic activity of HRMEC. G25/G50 showed a stimulatory effect on angiogenic tube formation in the Matrigel assay. (a) HREMCs were cultured on Matrigel, and the cumulative numbers of circle-like structures (yellow arrow) and branch points were measured after 9 h. (b) The vasculogenic capacity was quantified in cells treated with different groups. Con-5.5, G25, and G50: concentration of glucose (5.5, 25, and 50 mmol/l, respectively). Tube formation assay was examined under an inverted fluorescence microscope with a ×10 objective. HRMEC: human retinal vascular endothelial cells. 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Journal of Diabetes Research

fig4

Figure 4

Figure 4: An <i>In Vitro</i> Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration 

Journal of Diabetes Research

An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration

Figure 4