An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration

Table 1

Neurite extensions in RGCs detected by immunofluorescence staining at 48 h.

Groups	The proportion of RGCs with neurite extensions (%)	value
Con		—
G25		0.007^a
G50		<0.001^a
G100		<0.001^a
G150		<0.001^a
M25	51 (42-55)	0.691^b
M50		0.297^b
M100		0.716^a
M150		0.356^a

Statistically significant: . According to the type of data and the data distribution, ^aindependent-sample -test and the ^bMann-Whitney test were applied. Con-5.5, G25-G150: concentration of glucose (5.5, 25, 50, 100, and 150 mmol/l, respectively); M25-M150: concentration of M-mannitol (19.5, 44.5, 94.5, and 133.5 mmol/l, respectively). RGCs: retinal ganglion cells.