Pigment Epithelium-Derived Factor-Loaded PEGylated Nanoparticles as a New Antiangiogenic Therapy for Neovascularization

Table 1

Summary of proliferation effects with PEDF and NP-PEG-PEDF-treated HUVECs under high glucose (30 mmol/L).

Time points		10%FBS	NP-PEG	PEDF			NP-PEG-PEDF
			1000 ng/mL	1000 ng/mL	100 ng/mL	10 ng/mL	1000 ng/mL	100 ng/mL	10 ng/mL
24 h	Mean	1	94.27	80.33	77.34	69.15	54.19	45.83	40.34
	SEM		5.41	5.90	2.97	7.25	4.39	4.33	8.92
48 h	Mean	1	91.49	78.26	79.23	80.22	58.13	67.12	61.29
	SEM		6.87	3.69	4.89	5.32	5.02	3.71	10.23
72 h	Mean	1	91.12	83.89	86.13	88.3	64.29	63.12	59.56
	SEM		4.23	4.97	5.65	7.21	3.27	3.92	13.21