Current Studies on Molecular Mechanisms of Insulin Resistance

Table 1

Association with gene polymorphism of PC-1 (K121Q) with insulin resistance or T2D in various populations.

Association with gene polymorphism of PC-1 (K121Q)	Population	Reference
Associated with T2D	Ukrainian	[36]
Associated with T2D	South African mixed-ancestry population	[38]
Associated with insulin resistance	North Indian	[37]
Associated with T2D susceptibility	Chinese	[39, 40]
Associated with T2D risk	American, European and African	[41]
Increased susceptibility to diabetic kidney disease	European and Asian	[42]
Enhanced susceptibility to coronary artery disease	South Indian patients with T2D	[50]
Associated with T2D	Zanjan	[43]
No association with T2D	Lebanese and Tunisian	[46]
No association with T2D or obesity	Chinese	[47, 48]
No association with insulin resistance in T2D	Pakistani Punjabi	[44]
No association with T2D	Malaysian	[45]
No association with insulin resistance or T2D	Danish Caucasians	[49]