The Association of Sarcopenia and Visceral Obesity with Lean Nonalcoholic Fatty Liver Disease in Chinese Patients with Type 2 Diabetes Mellitus

Table 3

Subgroup analysis between sarcopenia and prevalent lean nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus.

	Lean NAFLD (%)	Sarcopenia (%)	OR	95% CI	value	for interaction
All	369/1,112 (33.18%)	290/1,112 (26.08%)	2.30	1.65-3.21	<0.001
Gender						0.630
Men	197/641 (30.73%)	205/641 (31.98%)	2.46	1.61-3.76	<0.001
Female	172/471 (36.52%)	85/471 (18.05%)	1.86	1.04-3.33	0.035
Age						0.528
≤65 years	323/978 (33.03%)	235/978 (24.03%)	2.21	1.54-3.19	<0.001
>65 years	46/134 (34.33%)	55/134 (41.04%)	2.78	1.11-7.00	0.029
Diabetes durations (median)						0.309
<76.5 months	205/556 (36.87%)	144/556 (25.90%)	1.87	1.14-3.08	0.014
≥76.5 months	164/556 (29.50%)	146/556 (26.26%)	3.04	1.89-4.88	<0.001
Visceral obesity						0.805
	194/767 (25.29%)	97/767 (12.65%)	2.10	1.24-3.58	0.006
	175/345 (50.72%)	193/345 (55.94%)	1.84	1.14-2.98	0.013
High BPs						0.595
<140/90 mmHg	255/810 (31.48%)	186/810 (22.96%)	2.26	1.50-3.41	<0.001
≥140/90 mmHg	114/300 (38.00%)	103/300 (34.33%)	2.30	1.24-4.25	0.008
Dyslipidemia						0.076
No	43/205 (20.98%)	44/205 (21.46%)	5.58	2.22-14.01	<0.001
Yes	323/901 (35.85%)	244/901 (27.08%)	2.12	1.47-3.04	<0.001

Adjusted for age, gender, SBP, DBP, HOMA-IR, TG, HDL-c, LDL-c, BMI, WC, diabetes durations, and smoking status. Abbreviations: lean NAFLD: lean nonalcoholic fatty liver disease; VFA: visceral fat area; BPs: blood pressures; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; BMI: body mass index; WC: waist circumference.