A Low Free T3 to Free T4 Ratio Is Associated with Sarcopenia in Euthyroid Patients with Type 2 Diabetes Mellitus

Table 1

Participants’ baseline characteristics, classified based on whether or not they had sarcopenia.

Characteristics	T2DM	T2DM+sarcopenia	value
Number	228 (73.1%)	84 (26.9%)
Female (, %)	105 (46.50%)	35 (41.7%)	0.490
Age (years)			<0.001
BMI (kg/m^2)			<0.001
Duration of T2DM (years)			<0.001
Hypertension (, %)	111 (48.7%)	50 (59.5%)	0.089
Smoking habit (, %)	47 (20.6%)	14 (16.7%)	0.436
Drinking habit (, %)	52 (22.8%)	19 (22.6%)	0.972
FCP (ng/mL)			0.012
Fins (μIU/mL)			0.465
FBG (mmol/L)			0.269
HbA1c (%)			0.170
HOMA-IR			0.653
TC (mmol/L)			0.431
TG (mmol/L)			0.014
HDL (mmol/L)			0.008
LDL (mmol/L)			0.366
eGFR (mL/min/1.73 m^2)			0.041
Waist-hip ratio			0.013
Body fat percentage (%)			0.605
SMI (kg/m^2)			<0.001
FT3 (pmol/L)			0.008
FT4 (pmol/L)			0.044
FT3/FT4			0.001
TSH (μIU/mL)			0.268
Low muscle mass (, %)	52 (22.8%)	84 (100%)	<0.001
Low muscle strength (, %)	33 (14.5%)	44 (52.4%)	<0.001
Low gait speed (, %)	75 (32.9%)	76 (90.5%)	<0.001

Notes: data are reported as mean (SD), median (interquartile range), or count (percentage), depending on the variable type. Abbreviations: T2DM: type 2 diabetes mellitus; BMI: body mass index; FBG: fasting blood glucose; FCP: fasting C peptide; Fins: fasting insulin; HbA1c: hemoglobin A1c; HOMA-IR: homeostatic model assessment of insulin resistance; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; eGFR: estimating glomerular filtration rate; SMI: skeletal muscle index; FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid-stimulating hormone. .