A Low Free T3 to Free T4 Ratio Is Associated with Sarcopenia in Euthyroid Patients with Type 2 Diabetes Mellitus

Table 2

Logistic regression analysis of thyroid hormones and sarcopenia.

Independent variable	Model 1		Model 2		Model 3
	OR (95% CI)		OR (95% CI)		OR (95% CI)
FT3, per 1 pmol/L	0.556 (0.355-0.870)	0.010	0.562 (0.342-0.922)	0.023	0.522 (0.304-0.895)	0.018
FT4, per 1 pmol/L	1.108 (1.002-1.224)	0.046	1.123 (1.008-1.252)	0.035	1.126 (1.009-1.258)	0.034
FT3/FT4, per 0.01 unit	0.931 (0.892-0.972)	0.001	0.926 (0.883-0.970)	0.001	0.923 (0.879-0.969)	0.001
TSH, per 1 μIU/mL	0.863 (0.665-1.120)	0.268	0.901 (0.686-1.183)	0.455	0.901 (0.679-1.197)	0.473

Notes: model 1, unadjusted; model 2, adjusted for age, gender, smoking habit, drinking habit, duration of DM, hypertension, and HbA1c; model 3, adjusted for age, gender, smoking habit, drinking habit, duration of DM, hypertension, HbA1c, eGFR, TG, HDL-C, and body fat percentage. Abbreviations: FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid-stimulating hormone; OR: odds ratio; CI: confidence interval. .