Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway

Table 1

General information in DK patients.

	NC	NDK	DK	value
	38	56	81	—
Age				0.18
Gender (male/female)	21/17	31/25	51/32	0.11
Course (years)	0.00 (0,0)	9.00 (4,16)^a	5.00 (0,7)^ab	<0.01
FPG (mmol/l)		^a	^ab	<0.01
HbA1c (%)		^a	^ab	<0.01
TP (g/l)				0.48
ALB (g/l)			^ab	0.04
ALT (IU/l)				0.29
AST (IU/l)				0.12
TBIL (μmol/l)				0.77
IBIL (μmol/l)				0.45
DBIL (μmol/l)				0.66
GGT (IU/L)				0.75
TG (mmol/l)			^a	0.08
TC (mmol/l)			^a	0.06
HDL-C (mmol/l)				0.88
LDL-C (mmol/l)			^a	0.01
Na^+ (mmol/l)				0.91
K^+ (mmol/l)			^a	<0.01
POP (mmol/l)				0.21
BUN (mmol/l)			^a	<0.01
eGFR (ml/min.1.73m^2)		^a	^ab	<0.01
sCr (μmol/l)				0.62
sUA (μmol/l)		^a	^a	0.05

ALB: albumin; ALT: alanine aminotransferase; AST: aspartate transaminase; BUN: blood urea nitrogen; DBIL: direct bilirubin; DK: diabetic ketosis; eGFR: estimated glomerular filtration rate; FPG: fasting plasma glucose; GGT: glutamyltransferase; HbA1c: glycated hemoglobin; HDL-C: high-density lipoprotein cholesterol; IBIL: indirect bilirubin; LDL-C: low-density lipoprotein cholesterol; NC: normal control; NDK: nondiabetic ketosis; POP: plasma osmotic pressure; SCr: serum creatinine; SUA: serum uric acid; TBIL: total bilirubin; TC: total cholesterol; TG: triglyceride; TP: total protein. Data are expressed as . ^aCompared with NC, ; ^bcompared with NDK, .