Journal of Diabetes Research / 2022 / Article / Tab 3 / Research Article
Efficacy and Safety of Dapagliflozin versus Liraglutide in Patients with Overweight or Obesity and Type 2 Diabetes Mellitus: A Randomised Controlled Clinical Trial in Tianjin, China Table 3 Changes in other metabolic indicators (body weight, Tg, LDL-C, DBP, and SBP) at week 24.
Parameter Liraglutide Dapagliflozin Body weight (kg) Baseline Week 24 Change from baselinea -0.08 (-1.78~1.94) -0.61 (-1.23~0.01) value -0.086 1.939 value 0.931 0.055 SBP (mmHg) Baseline Week 24 Change from baselinea -3.98 (-8.87~0.92) -5.28 (-8.43~-2.12) value 1.608 3.306 value 0.111 0.001 DBP (mmHg) Baseline Week 24 Change from baselinea 0.38 (2.92~-1.28) -1.12 (-2.91~0.67) value -0.296 1.233 value 0.767 0.220 Tg (mmol/l) Baseline Week 24 Change from baselinea -0.24 (-0.49~0.01) -0.15 (-0.49~0.18) value 1.974 0.907 value 0.053 0.367 LDL-C (mmol/l) Baseline Week 24 Change from baselinea -0.24 (-0.49~0.02) -0.24 (-0.42~-0.05) value 1.837 2.512 value 0.071 0.014
Abbreviations: SBP: systolic blood pressure; DBP: diastolic blood pressure; Tg: triglycerides; LDL-C: low-density lipoprotein cholesterol. a Mean change (95% confidence interval).