Research Article

Comparable Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass on Basal Fuel Metabolism and Insulin Sensitivity in Individuals with Obesity and Type 2 Diabetes

Table 1

Baseline characteristics.

CTSRYGBSG value

Female sex, no. (%)4 (50)9 (100)3 (43),
Age (years)49.3 (27 66)59.7 (37 58)47.4 (39 51)
T2D duration (years)2.8 (0.4 6)1.5 (0.1 4)
Weight (kg)74.1 (59 98)117.3 (94 144)126.8 (95 149),
BMI (kg/m2)25.1 (23 27)41.9 (33 50)41.6 (35 48),
LBM (kg)49.9 (35 68)60.5 (52 72)71.7 (50 88),
FM (kg)24.2 (21 33)54.9 (36 77)53 (44 64),
FM (%)32.5 (26 38)46.5 (38 54)42 (35 51),
HbA1c (mmol/mol)35.25 (28 40)51.8 (45 59)52.9 (44 64),

Data are expressed as mean (range). For comparisons, an analysis of variance (ANOVA) or a nonparametric Kruskal-Wallis test was applied. Post hoc tests were performed when appropriate, with an unpaired -test. For dichotomous values, we used Fischer’s exact test. Comparisons: CTS vs. RYGB, CTS vs. SG, and RYGB vs. SG. Abbreviations: CTS: control subjects; RYGB: Roux-en-Y gastric bypass group; SG: sleeve gastrectomy group; BMI: body mass index; LBM: lean body mass; FM: fat mass; HbA1c: glycated haemoglobin.