Journal of Diabetes Research

Research Article

Correlation between Acylcarnitine and Peripheral Neuropathy in Type 2 Diabetes Mellitus

Table 2

Acylcarnitine profile in T2DM patients.


Variables	DPN	Non-DPN
Variables	Median (interquartile range)	Median (interquartile range)

C0	25.09 (20.18, 32.43)	25.64 (20.38, 31.80)	0.252
C2	10.63 (7.95, 13.59)	9.65 (7.04, 12.71)	0.012
C3	1.52 (1.12, 2.02)	1.45 (1.03, 2.09)	0.602
C4	0.18 (0.14, 0.23)	0.18 (0.13, 0.24)	0.605
C4-OH	0.04 (0.03, 0.07)	0.05 (0.03, 0.08)	0.001
C4DC	0.29 (0.22, 0.41)	0.33 (0.24, 0.46)	0.006
C5	0.15 (0.11, 0.20)	0.16 (0.12, 0.20)	0.959
C5-OH	0.18 (0.14, 0.24)	0.20 (0.15, 0.28)	0.001
C5DC	0.05 (0.03, 0.09)	0.06 (0.04, 0.09)	0.124
C5:1	0.04 (0.02, 0.05)	0.04 (0.02, 0.06)	0.145
C6	0.07 (0.05, 0.09)	0.07 (0.05, 0.08)	0.289
C8	0.05 (0.04, 0.08)	0.06 (0.04, 0.09)	0.001
C10	0.05 (0.03, 0.07)	0.06 (0.03, 0.09)	0.007
C12	0.05 (0.03, 0.07)	0.05 (0.03, 0.07)	0.543
C14	0.05 (0.04, 0.07)	0.06 (0.04, 0.08)	0.047
C14-OH	0.02 (0.01, 0.04)	0.03 (0.02, 0.04)	0.109
C14DC	0.02 (0.02, 0.04)	0.02 (0.01, 0.04)	0.906
C16	0.73 (0.58, 0.95)	0.72 (0.55, 0.91)	0.437
C16-0H	0.02 (0.01, 0.03)	0.02 (0.02, 0.04)	0.010
C16:1-OH	0.04 (0.03, 0.05)	0.04 (0.03, 0.05)	0.390
C18	0.44 (0.32, 0.55)	0.43 (0.33, 0.59)	0.652
C20	0.02 (0.01, 0.03)	0.02 (0.02, 0.03)	0.004
C22	0.04 (0.03, 0.06)	0.05 (0.03, 0.07)	0.050
C24	0.03 (0.02, 0.05)	0.04 (0.03, 0.05)	0.022
C26	0.03 (0.02, 0.03)	0.03 (0.02, 0.04)	0.589
C14:1	0.05 (0.03, 0.07)	0.05 (0.03, 0.07)	1.000

C0 = free carnitine; C2 = acetylcarnitine; C3 = propionylcarnitine; C4 = butyrylcarnitine; C4-OH = hydroxylbutyrylcarnitine; C4DC =succinylcarnitine; C5 = isovalerylcarnitine; C5-OH = 3-hydroxyisovalerylcarnitine; C5DC = glutarylcarnitine; C5:1 = tiglylcarnitine; C6 = hexanoylcarnitine; C8 = octanoylcarnitine; C10 = decanoylcarnitine; C12 = lauroylcarnitine; C14 = myristoylcarnitine; C14-OH = 3-hydroxyl-tetradecanoylcarnitine; C14DC = tetradecanoyldiacylcarnitine; C14:1 = tetradecenoylcarnitine; C16 = palmitoylcarnitine; C16-OH = 3-hydroxypalmitoylcarnitine; C16 = 1-OH, 3-hydroxypalmitoleylcarnitine; C18 = octadecanoylcarnitine; C20 = arachidic carnitine; C22 = behenic carnitine; C24 = tetracosanoic carnitine; C26 = hexacosanoic.