Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus
Table 1
Characteristics of CHD cases and controls.
Characteristic
CHD group ()
Control group ()
value
Male patients (%)
188 (63.3)
78 (40.0)
<0.001
Age
64 (58–72)
62 (55–70)
0.031
Diabetic duration (years)
7 (3–12)
7 (2–12)
0.579
Antidiabetics medication (%)
265 (89.22)
180 (92.3)
0.544
Hypertension history (%)
77.4
76.9
0.893
Antihypertensive medication (%)
204 (68.69)
135 (69.23)
0.981
FPG (mmol/L)
6.34 (5.45–8.13)
6.52 (5.51–8.52)
0.377
HbA1c(%)
6.83 (6.40–7.80)
6.80 (6.20–7.58)
0.155
TG (mmol/L)
1.42 (0.97–1.95)
1.43 (1.02–2.05)
0.585
TC (mmol/L)
3.84 (3.37–4.64)
4.02 (3.50–4.70)
0.196
LDL-c (mmol/L)
2.25 (1.87–2.81)
2.30 (1.83–2.81)
0.828
HDL-c (mmol/L)
0.94 (0.80–1.09)
1.04 (0.88–1.20)
<0.001
Use of statins
113(38.05)
83(42.56)
0.481
BMI (kg/m2)
0.313
Smoking (%)
48.8
33.9
0.001
Data are presented as the , median (interquartile range), or (%). values were obtained using the independent-samples t test, Mann–Whitney U test, or test. BMI: body mass index; FPG: fasting plasma glucose; TG: triglycerides; TC: total cholesterol; LDL-c: low-density lipoprotein cholesterol; HDL-c: high-density lipoprotein cholesterol.