Research Article

Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus

Table 1

Characteristics of CHD cases and controls.

CharacteristicCHD group ()Control group () value

Male patients (%)188 (63.3)78 (40.0)<0.001
Age64 (58–72)62 (55–70)0.031
Diabetic duration (years)7 (3–12)7 (2–12)0.579
Antidiabetics medication (%)265 (89.22)180 (92.3)0.544
Hypertension history (%)77.476.90.893
Antihypertensive medication (%)204 (68.69)135 (69.23)0.981
FPG (mmol/L)6.34 (5.45–8.13)6.52 (5.51–8.52)0.377
HbA1c(%)6.83 (6.40–7.80)6.80 (6.20–7.58)0.155
TG (mmol/L)1.42 (0.97–1.95)1.43 (1.02–2.05)0.585
TC (mmol/L)3.84 (3.37–4.64)4.02 (3.50–4.70)0.196
LDL-c (mmol/L)2.25 (1.87–2.81)2.30 (1.83–2.81)0.828
HDL-c (mmol/L)0.94 (0.80–1.09)1.04 (0.88–1.20)<0.001
Use of statins113(38.05)83(42.56)0.481
BMI (kg/m2)0.313
Smoking (%)48.833.90.001

Data are presented as the , median (interquartile range), or (%). values were obtained using the independent-samples t test, Mann–Whitney U test, or test. BMI: body mass index; FPG: fasting plasma glucose; TG: triglycerides; TC: total cholesterol; LDL-c: low-density lipoprotein cholesterol; HDL-c: high-density lipoprotein cholesterol.