Research Article

Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus

Table 2

Allele distribution of five SIRT1 tag SNPs between the CHD and control groups.

SNPsAlleleCHD group (%)Control group (%)OR (95% CI) value

rs16924934A476 (81.2)334 (86.1)1
G110 (18.8)54 (13.9)1.429 (1.003–2.037)0.048
rs3818292A402 (69.3)277 (71.4)1
G178 (30.7)111 (28.6)1.105 (0.833–1.465)0.488
rs12242965C467 (78.6)317 (81.1)1
T127 (21.4)74 (18.9)1.165 (0.846–1.605)0.350
rs3818291G515 (86.7)350 (89.7)1
A79 (13.3)40 (10.3)1.342 (0.896–2.010)0.152
rs4746720T343 (57.7)218 (55.9)1
C251 (42.3)172 (44.1)0.927 (0.717–1.200)0.567

The test was used to evaluate significance.