Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus

Table 4

Dominant inheritance model of the distribution between CHD and control groups.

SNP	Genotype	CHD group (%)	Control group (%)	OR (95% CI)		OR’ (95% CI’)
rs16924934	A/A	185 (63.1)	140 (72.2)	1
	A/G + G/G	108 (36.9)	54 (27.8)	1.514 (1.021–2.243)	0.039	1.496 (0.985–2.272)	0.059
rs3818292	A/A	129 (44.5)	94 (48.5)	1
	A/G + G/G	161 (55.5)	100 (51.5)	1.173 (0.815–1.689)	0.391	1.184 (0.804–1.743)	0.391
rs12242965	C/C	178 (59.9)	129 (66.2)	1
	C/T + T/T	119 (40.1)	66 (33.8)	1.307 (0.897–1.904)	0.164	1.287 (0.863–1.919)	0.216
rs3818291	G/G	220 (74.1)	158 (81.0)	1
	G/A + A/A	77 (25.9)	37 (19.0)	1.495 (0.961–2.326)	0.075	1.555 (0.967–2.501)	0.069
rs4746720	T/T	89 (30.0)	54 (27.7)
	T/C + C/C	208 (70.0)	141 (72.3)	0.895 (0.6–1.335)	0.587	0.88 (0.574–1.349)	0.557

, , and were determined after adjusting for age, sex, smoking status, and HDL-c levels by logistic regression analysis.